Ketogenic Diets And Alzheimer’s

The Alzheimer’s Association reports that almost 6 million Americans live with Alzheimer’s. Additionally, someone develops the disease every 65 seconds. There is a dire need for solutions.

Diabetic Patient

Particularly, a good support network is crucial to the management of the disease. To date, 16 million Americans provide unpaid care for people with Alzheimer’s. However, it is important to consider the terrible toll the disease takes on caregivers.

Yet, there is hope in more ways than one. Researchers continue to make new research advancements and to uncover promising developments in treatment options.

The Importance of Insulin

According to Clinical Neurology News, insulin plays a key role in brain function, glucose metabolism, and amyloid beta/tau regulation. Amyloid beta and tau buildup can damage brain cells responsible for memory and cognition. So, insulin plays a critical role in regulating the accumulation of amyloid and tau.

At the 2017 World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease, Suzanne Craft, PhD explained the importance of insulin. After insulin crosses the blood-brain barrier, it binds to receptors and modulates important brain functions. However, it is now known that modulation malfunctions can result in insulin resistance and, ultimately, Alzheimer’s disease.

Today, doctors use intranasal insulin to treat patients with mild cognitive impairment and Alzheimer’s disease. However, a new, non-pharmacological approach has also shown promise – the ketogenic diet.

How A Ketogenic Diet Can Help Alzheimer’s Patients

The ketogenic diet is a high fat, low carbohydrate diet. Its benefit are found in how it depletes the body of excess sugar. Many health experts argue that it should be an important part of a healthy lifestyle. Additionally, researchers speculate that the unique diet may be effective in treating Alzheimer’s disease.

Dr. Craft’s research team divided 87 middle-aged people into two groups. One ate a high salt, sugar, and saturated fat Western diet. Meanwhile, the other group ate a healthier diet.

Not surprisingly, those on the Western diet showed reduced memory and blood flow after 4 weeks. Meanwhile, participants in the healthy diet showed increased blood flow to several regions of the brain. They also reported improved memory function. The results were significant.

Personalized, Compassionate Care at David York Agency

At David York, we understand the toll Alzheimer’s takes on caregivers. So, if someone you love requires full-time or part-time care at home, contact us. Our healthcare professionals can provide personalized, compassionate care to your loved one. They can assist with everything from meal preparation to companionship.

Halting Alzheimer’s Disease: How Controlling Inflammation Could Be the Key

Alzheimer's Disease

The Alzheimer’s Association estimates that approximately 5.3 million Americans are afflicted with Alzheimer’s disease. Currently, one in three seniors will die from Alzheimer’s or some other form of dementia. Such staggering statistics may seem dismal, but there is hope on the horizon with recent research findings.

Researchers from the University of Southampton in England have been working with a chemical that reduces neuroinflammation in the brain. This chemical may help protect against the memory and behavioral changes associated with Alzheimer’s.

How Inflammation Plays a Part in Alzheimer’s

It is theorized that an overactive immune system causes chronic inflammation in the brain. Though researchers are not sure, they suspect that the inflammation is a catalyst for the disease rather than the other way around.  Scientists have linked that inflammation to Alzheimer’s in several clinical studies where they have looked at the tissue of a healthy brain versus one afflicted by Alzheimer’s. The brains that suffered from Alzheimer’s showed high levels of immune cells (microglia) and the concentration of these cells were greater as the disease increased in severity thereby suggesting chronic brain inflammation in Alzheimer’s sufferers. The molecules that regulate the number of immune cells clearly became more active as the severity of Alzheimer’s in the brains increased clustering around the amyloid plaques in the brain associated with the disease. The inflammation is believed to not be a result of the Alzheimer’s disease but a key driver of the disease, states a report done by the Huffington Post.

The National Health Service (NHS) reports that mice suffering from symptoms similar to Alzheimer’s experienced improvement when given a drug with the chemical GW2580, which blocked the production of the microglial immune cells that caused brain inflammation. However, the prevalence of amyloid plaques was not diminished.  Research in the mice showed an improvement in the cognitive and behavioral symptoms relating to Alzheimer’s when fed GW2580 thereby inhibiting immune cell production and reducing the inflammation within the brain.

Currently, researchers are very hopeful that controlling inflammation in the brain of Alzheimer’s sufferers, through the use of medication, diet and lifestyle changes, has the potential to significantly reduce memory loss caused by the disease, along with a variety of other Alzheimer’s symptoms.

At David York Agency, we understand the fears and challenges that Alzheimer’s disease can bring, not just for the person diagnosed, but for everyone in their life. We hope to provide families with the support and care they need during this particularly difficult time.

For more information about David York Agency’s qualified, compassionate caregivers, contact us at 718.376.7755. A free consultation can help you decide what services might be best to provide you and your loved one with the assistance they need. If you’d like to hear more from us, please like us on Facebook or follow us on Twitter, Google+ or LinkedIn.