Exercise & Alzheimer’s Disease Prevention

Exercise May Prevent Alzheimer’s Disease

The New York Times just reported on a fascinating study published in the May edition of Frontiers in Aging Neuroscience in an article entitled, “Can Exercise Reduce Alzheimer’s Risk?” by Gretchen Reynolds. By examining people aged 65-89 who possess a gene related to Alzheimer’s development, e4 gene, they have found a connection. They have confirmed their hypothesis. Even moderate amounts of exercise or physical activity can help to slow the progression of Alzheimer’s disease.

Exercise and Alzheimer's DiseaseThe study was based on relating the following factors:

  • Researchers suspect that it takes years for Alzheimer’s to actually present symptoms in patients.
  • People with the e4 gene have a higher risk for Alzheimer’s Disease.
  • Elderly people with the e4 gene who exercised showed better brain functioning than those who did not exercise.
  • Brains of people with Alzheimer’s have hippocampi, a part of the brain necessary for memory processing, that are more shrunken when compared to those in similar age groups without the disease.

The study divided almost 100 men and women between 65-89 years of age into four groups:

  1. Those who have the e4 gene and do exercise.
  2. Those with the e4 gene that do not exercise.
  3. Those who do not have the gene and do exercise.
  4. Those who do not have the gene and do not exercise.

Exciting Results

After 18 months, the group who had the e4 gene and exercised had the same normal hippocampi as the two groups who did not have the gene. At the same time, the group who had the e4 gene and did not exercise saw significant atrophy.  Obviously, this has tremendous implications for those who have the e4 gene.  An exercise regimen is an absolute must for those who have the e4 gene. Furthermore, we must incorporate exercise way before any signs and symptoms of Alzheimer’s appear.

Whether you have the e4 gene or even just a family history of Alzheimer’s or neither, the conclusion is clear. With all the research indicating the benefit of exercise, it would seem prudent on many levels to incorporate it into your weekly routine.


David York Agency is well versed in the treatment of Alzheimer’s Disease in the elderly. Our home health aides and home healthcare team are adept at in-home senior care.  Please call us at (718) 376-7755 or visit us at our website www.davidyorkagency.com and we would be happy to give you more information about our elder care services.  You can also like us on Facebook or follow us on Twitter or LinkedIn.